Feasibility and acceptability of integrating hepatitis B care into routine HIV services: a qualitative study among health care providers and patients in West Nile region, UgandaArticle Published on 2023-01-202023-06-12 Journal: BMC health services research [Category] B형 간염, [키워드] feasibility hepatitis B HIV integration Uganda. [DOI] 10.1186/s12913-022-08924-0 PMC 바로가기
Diffusion-Induced Ingress of Angiotensin-Converting Enzyme 2 into the Charge Conducting Path of a Pentacene Channel for Efficient Detection of SARS-CoV-2 in Saliva SamplesArticle Published on 2022-10-282022-11-15 Journal: ACS Sensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] accelerate ACE2 angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 (ACE2) biosensor can be used channel charge Conducting correlation COVID-19 detection diagnostic test disease efficient false-negative field-effect transistor. gold standard growth handling highest integration Laboratory Large-scale testing less medium molecular Organic field-effect transistor path pathogen platform POC point-of-care Rapid receptor remote monitoring reported Saliva Sample SARS-CoV-2 sensitivity specimens Spread statistical analysis the disease the epidemic the SARS-CoV-2 virus the spike protein transfer Viral RNA viral titer virus [DOI] 10.1021/acssensors.2c01287 PMC 바로가기
Toward Next Generation Lateral Flow Assays: Integration of NanomaterialsArticle Published on 2022-09-282022-11-15 Journal: Chemical reviews [Category] Fulltext, MERS, 진단, [키워드] Bacterial complex COVID-19 diagnostic diagnostics feasibility Flow Generation highlight inherent integration Lateral limitation limits Nanomaterial pesticide platform point-of-care pregnancy test quantification receptor review sensitivity [DOI] 10.1021/acs.chemrev.1c01012 PMC 바로가기
Integration of Power-Free and Self-Contained Microfluidic Chip with Fiber Optic Particle Plasmon Resonance Aptasensor for Rapid Detection of SARS-CoV-2 Nucleocapsid ProteinArticle Published on 2022-09-232022-11-15 Journal: Biosensors [Category] SARS, 변종, 치료기술, 치료제, [키워드] antigen detection aptamer binding binding kinetics COVID-19 detect detection diagnostic fiber fiber optic biosensor global pandemic Gold nanoparticle infectious viruses integration leaking limit of detection localized surface plasmon resonance marker Microfluidic chip mutants N-protein novel coronavirus SARS-CoV-2 nucleocapsid nucleocapsid protein Optic Particle Plasmon POCT point-of-care Point-of-care testing. Rapid resonance risk robust SARS-CoV-2 single-stranded DNA ssDNA structural protein the SARS-CoV-2 the WHO virus [DOI] 10.3390/bios12100785 PMC 바로가기
Integration of Multiple Interferometers in Highly Multiplexed Diagnostic KITs to Evaluate Several Biomarkers of COVID-19 in SerumArticle Published on 2022-08-232022-11-15 Journal: Biosensors [Category] SARS, 바이오마커, 진단, 치료기술, [키워드] Biomarker Biomarkers carried collected COVID-19 COVID-19 biomarkers CRP detection diagnostic evaluate evaluated FER ferritin IgGs Immunoglobulin inflammatory disorders integration Interferometer interferometric optical detection method investigated involved KIT mild patient Model moderate Multiple optical PCR polymerase chain positive Regression SARS-CoV-2 serum serum sample serum. Spain specific biomarker [DOI] 10.3390/bios12090671 PMC 바로가기
Portable Electrochemical Biosensors Based on Microcontrollers for Detection of Viruses: A Review바이러스 검출을 위한 마이크로컨트롤러 기반 휴대용 전기화학 바이오센서: 리뷰Review Published on 2022-08-222022-09-11 Journal: Biosensors [Category] 치료기술, [키워드] alternative amperometry amplification analyte biosensor can be used costly COVID-19 pandemic current Cycling detection detection technique Diagnostic method diagnostic methods diagnostics DNA amplification Early detection electrochemical biosensors Electrochemical impedance spectroscopy element elements explained integration Isolation lab Laboratory Microcontroller Microfluidics mitigate Modification offer Outbreaks pandemic patients point-of-care potentiostat producing Rapid test respiratory viruses review RT-LAMP RT-PCR transducer turnaround time virus virus virus detection Voltammetry. zoonotic disease [DOI] 10.3390/bios12080666 PMC 바로가기 [Article Type] Review
Notes from an epicenter: navigating behavioral clinical trials on autism spectrum disorder amid the COVID-19 pandemic in the BronxRandomized Controlled Trial Published on 2022-08-192022-10-05 Journal: Trials [Category] 임상, [키워드] adjust Applied behavior analysis autism spectrum Autism Spectrum Disorder autistic Behavioral intervention children clinical trial COVID-19 COVID-19 pandemic disorder event functional impacted increasingly integration offer pandemic participant presenting primary outcome measure protocol Randomized controlled trial RCT recruitment Research resource risk Sensory Sensory integration therapy. Study protocol sustained therapy unique utility [DOI] 10.1186/s13063-022-06635-9 PMC 바로가기 [Article Type] Randomized Controlled Trial
Metacells untangle large and complex single-cell transcriptome networksMetacells는 크고 복잡한 단일 세포 전사체 네트워크를 풉니다.Article Published on 2022-08-132022-09-11 Journal: BMC Bioinformatics [Category] 유전자 메커니즘, [키워드] accelerate analysis build Cell cell type cell type annotation cells Clustering Coarse-graining complex Computational biology construction correlation COVID-19 patient COVID-19 patients demonstrated develop differential expression downstream analyses downstream analysis facilitate framework heterogeneous IMPROVE imputation inherent integration Interpretation less Metacells offer populations redundancy RNA RNA sequencing scRNA-seq scRNA-seq data significantly single-cell Single-cell RNA sequencing Single-cell transcriptomics Single-cell transcriptomics. SuperCell tissue Transcriptome transcriptomic unique Visualization [DOI] 10.1186/s12859-022-04861-1 PMC 바로가기 [Article Type] Article
Defining resistance and tolerance traits in Covid-19: towards a stratified medicine approachCovid-19의 내성 및 내성 특성 정의: 계층화된 의학 접근 방식Article Published on 2022-08-132022-09-11 Journal: QJM: An International Journal of Medicine [Category] SARS, 변종, [키워드] activated anti-Spike IgG approach Auto-antibodies CCR2 component coronavirus disease Coronavirus disease 2019 COVID-19 pathogenesis Deleterious failure Genetic Genetic variant genotypic GM-CSF heterogeneity highlight Highlights Host Host-directed therapies Human IFN-I IFN-α IFNA10 IFNAR2 IL-6 infection with SARS-CoV-2 Infectious disease inflammasomes inflammatory lung injury integration Inter-individual variation life-threatening coronavirus disease lung Lung injury M-CSF macrophages MCP-1 Monocyte-derived macrophages Monocytes neutralizing auto-antibodies neutralizing auto-antibody NLRP1 pathogen Pathogenesis periphery PLSCR1 pro-inflammatory pro-inflammatory response progression recruited reduce regulate response responses resulting reticuloendothelial system SARS-COV-2 infection stratified the disease therapeutic tissue damage Tolerance treatable TYK2 type 1 interferon virus-independent immunopathology [DOI] 10.1093/qjmed/hcac143 PMC 바로가기 [Article Type] Article
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC studyResearch article Published on 2022-08-092022-10-05 Journal: EBioMedicine [Category] SARS, 바이오마커, 치료기술, [키워드] 7-point ordinal scale 95% CI age antibody assessment association baseline Better characteristics of patient chest imaging Cohort Comorbidities coronavirus disease COVID-19 creatinine death demographics discharge disease course disease severity Dyspnea elevated Factor female finding Follow-up funding Hispanic ethnicity hospital Hospitalization Hospitalized hospitalized COVID-19 Immunophenotyping IMPROVE integration interquartile range Invasive mechanical ventilation Laboratory Logistic regression longitudinal lowest lymphopenia management median age NIH Odds ratio offer outcome overall mortality PASC Patient PCR cycle provide Radiographic required Respiratory illness Result risk factor SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 PCR SARS-CoV2 serology severity Sex survivor Symptom Symptomatic patients The United States threshold Trajectories trajectory Unsupervised clustering Viral load was performed [DOI] 10.1016/j.ebiom.2022.104208 [Article Type] Research article